Custom Peptides
Cayman Chemical MOG35-55mouseratrI 10mg
An MOG antigen peptide; induces demyelination of the spinal cord, degeneration of the optic nerve, and visual impairments in mice in combination with heat-killed M. tuberculosis and CFA; has been used to induce EAE in animal models of multiple sclerosis in combination with adjuvants
Cayman Chemical NdSethyl BrInzolamIDoxal 10mg
An active metabolite of brinzolamide; inhibits CAII and CAIV activities (IC50s = 1.28 and 128 nM, respectively)
Cayman Chemical 1 2DIstearoyl3Oleoylracg 10mg
A triacylglycerol; has been found in cocoa butter and vegetable oils
Cayman Chemical PB22 NpentnoIc acId3carb 10mg
A potential metabolite of PB-22; intended for forensic and research purposes
Cayman Chemical 1 2DIlInoleoylsnglycerol 10mg
A DAG; has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes; upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in EArly pregnancy
Cayman Chemical 5fluoro PB22 8hdroxIsoqu 10mg
Differs from 5-fluoro PB-22 by having the quinoline group replaced with an isoquinoline group attached at its eight position; intended for forensic and research purposes
Cayman Chemical TPT-260hydrochlorIde 10mg
A thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~5 µM); dose-dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of pathogenic APP in cultured hippocampal neurons
Cayman Chemical 1mthyl1 4dIhydronIcotInam 10mg
A nicotinamide derivative; inhibits β-elimination activity of hSR (IC50 = 177 μM)
Cayman Chemical 6a-ProstaglndIn I1 10mg
6α-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6α-PGI1 promotes cAMP accumulation in human thyroid slices and cells in a concentration dependent manner. However, it is about 10-fold less potent than the β-isomer and 100-fold less potent than PGI2 in eliciting the response.{11172} 6α-PGI1 exhibits an IC50 of 350 ng/ml for inhibition of ADP-induced platelet aggregation, which is nearly 900-fold higher than that observed for PGI2 (0.4 ng/ml).{11183}
Cayman Chemical TrnsportntrIfluoroacetate 10mg
A cell-penetrating peptide; has been used in the surface functionalization of liposomes for drug delivery in vitro and in vivo and for the delivery of fluorescent cargo in vitro
Cayman Chemical L-CycloserIn 10mg
An inhibitor of sphingolipid synthesis and aminotransferases; inhibits bacterial SPT 100 times more potently than D-cycloserine; inhibits SPT activity up to 86% in a dose-dependent manner in mouse brain microsomes following administration of doses ranging from 25-200 mg/kg; inhibits SPT in rabbit aorta and several aminotransferases in vitro and in vivo in rat; inhibits the growth of M. tuberculosis through branched chain aminotransferase inactivation, and it does so more rapidly and potently than D-cycloserine (MICs = 0.3 and 2.3 UG/ml, respectively)
Cayman Chemical 5-trns Fluprostenol 10mg
A potential impurity in commercial preparations of fluprostenol